4N6FLOQSWABS, an Alternative for Sample Collection

The 4N6FLOQSwabsTM have been proposed as a more effective swab for releasing cellular materials than cotton swabs due to its nylon fibers and lack of an inner core. The recovery of DNA from 4N6FLOQSwabsTM samples can be increased with the use of the Nucleic Acid Optimizer (NAOTM ). 4N6FLOQSwabs also are treated with an antimicrobial agent for direct storage of swabs after collection to improve DNA yield. Results showed that in our hands the 4N6FLOQSwabs provided statistically significant higher recovery of DNA than cotton swabs. Also, the antimicrobial activity of the 4N6FLOQSWABSTM was confirmed. Thus, the 4N6FLOQSWABSTM can be considered as a valid alternative to the most commonly used cotton swab to collect DNA evidence at crime scenes and in forensic laboratories.