Scientific Study Library
Thank you for visiting COPAN's Scientific Studies Library, your online resource for proof sources related to COPAN products as well as many other aspects of sample collection and transport, automation, food and pharmaceutical testing, forensic and genetic collection and more!
The Impact of Full Laboratory Automation
The latest issue of the Canadian Journal of Laboratory Science features the growing adoption of full laboratory automation in Clinical Microbiology. The article shows how one laboratory's implementation of WASPLab®and PhenoMATRIX® Artificial Intelligence enhanced their workflow, allowing laboratory professionals to focus on more complex and high-value tasks.
Comparison of Results Obtained with the FilmArray GI Panel using rectal Swabs and Cary-Blair Stool from Patients with Gastroenteritis in the Pediatric Emergency Department
Automated Scoring of Chromogenic Media for the Detection of MRSA Using the WASPLab Image Analysis Software
Comparison of the Copan ESwab System with an Agar Swab Transport System for Maintenance of Fastidious Anaerobic Bacteria Viability
The Future is Here: Artificial Intelligence in the Medical Laboratory
Introduction For decades, we have been speculating on how our world will change with new innovations and technology introduced to our workspaces. A 2021 survey of laboratory stakeholders found that 66% of respondents felt they would use artificial intelligence (AI) in the future, but were unsure on how. Perhaps this is why speculation on AI…Read More
Comparison between Perianal Swab and Stool Specimens for Detecting Colonization with Extended-Spectrum Beta-Lactamase-Producing and Fluoroquinolone-Resistant Enterobacterales
ABSTRACT Stool specimens are frequently used to detect gastrointestinal tract colonization with antimicrobial-resistant enteric bacteria, but they cannot be rapidly collected. Perianal swab specimens can be collected more quickly and efficiently, but data evaluating their suitability as a specimen type for this purpose are sparse. We performed selective culture for extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) and fluoroquinolone- resistant Enterobacterales (FQRE)…Read More
The Hidden Crisis in the Times of COVID-19: Critical Shortages of Medical Laboratory Professionals in Clinical Microbiology
ABSTRACT The COVID pandemic has put a spotlight on laboratory medicine,showcasing how vital diagnostic testing is for society and the health care system.It has also brought to light and accelerated the critical shortage of trainedand experienced laboratory personnel that has been felt for decades. The needfor laboratory professionals is expected to grow by 11% between…Read More
Total Laboratory Automation for Rapid Detection and Identification of Microorganisms and Their Antimicrobial Resistance Profiles
At a time when diagnostic bacteriological testing procedures have become more complexand their associated costs are steadily increasing, the expected benefits of Totallaboratory automation (TLA) cannot just be a simple transposition of the traditionalmanual procedures used to process clinical specimens. In contrast, automation shoulddrive a fundamental change in the laboratory workflow and prompt users to…Read More
Validation of the Colibrí Instrument for Automated Preparation of MALDI-TOF MS Targets for Yeast Identification
ABSTRACT Recently, Copan (Italy) introduced the Colibrí instrument for automated colonypicking and preparation of matrix-assisted laser desorption ionization–time of ﬂight (MALDI- TOF)target plates. Our study aimed to validate this system for yeasts as such testing has not beenperformed yet and is a missing link needed to implement the system for routine use. Fifty-ﬁveCandida strains were…Read More
Assessment of the Frequency of Coughing and Sneezing Triggered by Nasopharyngeal Swabbing in the Pandemic Setting
A variety of medical procedures are classified as aerosol generating. However there is no consensus on whether some procedures such as nasopharyngeal swabbing can generate aerosols. During specimen collection, the contact of the nasopharyngeal swab with the respiratory mucosa often triggers defense reflexes such as sneezing and coughing, which generate airborne particles. The accumulation and…Read More
Evaluation of Commercially Available Viral Transport Medium (VTM) for SARS-CoV-2 Inactivation and Use in Point-of-Care (POC) Testing
Abstract: Critical to facilitating SARS-CoV-2 point-of-care (POC) testing is assurance that viruses present in specimens are inactivated onsite prior to processing. Here, we conducted experiments to determine the virucidal activity of commercially available Viral Transport Mediums (VTMs) to inactivate SARS-CoV-2. Independent testing methods for viral inactivation testing were applied, including a previously described World Health…Read More
A review of nasopharyngeal swab and saliva tests for SARS‐CoV‐2 infection: Disease timelines, relative sensitivities, and test optimization
Abstract Testing is an essential part of containment of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic. This review summarizes studies for SARS‐CoV‐2 infection and testing. Nasopharyngeal samples are best at sensitivity detection, especially in early stages of disease and in asymptomatic individuals. Current swab processing involves a 100‐ to 1000‐fold dilution of the…Read More
Sample collection and transport strategies to enhance yield, accessibility, and biosafety of COVID-19 RT-PCR testing
Abstract Introduction. Non-invasive sample collection and viral sterilizing buffers have independently enabled workflows for more widespread COVID-19 testing by reverse-transcriptase polymerase chain reaction (RT-PCR). Gap statement. The combined use of sterilizing buffers across non-invasive sample types to optimize sensitive, accessible, and biosafe sampling methods has not been directly and systematically compared. Aim. We aimed to…Read More
Beyond COVID-19—will self-sampling and testing become the norm?
In the fight against COVID-19, the general population in many countries has not been empowered to pursue diagnostic testing, but rather has been a subject to often frustrating and inadequate testing capacity. Diagnostics have been a cornerstone of the COVID-19 response globally, because strategies to contain and respond to the pandemic rely primarily on case…Read More
Inactivation of SARS-CoV-2 virus in saliva using a guanidium based transport medium suitable for RT-PCR diagnostic assays
Abstract BackgroundUpper respiratory samples used to test for SARS-CoV-2 virus may be infectious and presenta hazard during transport and testing. A buffer with the ability to inactivate SARS-CoV-2 atthe time of sample collection could simplify and expand testing for COVID-19 to non-conventionalsettings. MethodsWe evaluated a guanidium thiocyanate-based buffer, eNAT™ (Copan) as a possible transportand inactivation…Read More
Rapid and accurate eXDR screening: use Xpert Carba-R with FecalSwab
ABSTRACT The FecalSwab® displays high performances for stool culture, but it was not assessed for carbapenemase-producing Enterobacterales (CPE) screening. We assess the performances of the Xpert Carba-R v2® with the FecalSwab®. Using a collection of 12 CPE strains, the limit of detection was assessed at 158 CFU/swab [interquartile range 93–589]. In 2019, 1540 swabs were…Read More
Some of the studies in this database are independent scientific studies performed by third parties, while some of the studies were partially or entirely funded by COPAN. In addition to peer reviewed research this library also contains posters, which were presented at various scientific meetings, and may not have been subject to peer review.
Some of the studies found here may contain information about off label product use. Studies, product claims and availability may vary from country to country, and they are subject to varying regulatory requirements. Always refer to product labeling, package inserts and safety data sheets for the appropriate use of the products.