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Scientific Study Library

Thank you for visiting COPAN's Scientific Studies Library, your online resource for proof sources related to COPAN products as well as many other aspects of sample collection and transport, automation, food and pharmaceutical testing, forensic and genetic collection and more!

Comparison of Results Obtained with the FilmArray GI Panel using rectal Swabs and Cary-Blair Stool from Patients with Gastroenteritis in the Pediatric Emergency Department

Automated Scoring of Chromogenic Media for the Detection of MRSA Using the WASPLab Image Analysis Software

Comparison of the Copan ESwab System with an Agar Swab Transport System for Maintenance of Fastidious Anaerobic Bacteria Viability

Automation in the Clinical Microbiology Laboratory

Latest Studies:

Comparison between Perianal Swab and Stool Specimens for Detecting Colonization with Extended-Spectrum Beta-Lactamase-Producing and Fluoroquinolone-Resistant Enterobacterales

August 2, 2022

ABSTRACT Stool specimens are frequently used to detect gastrointestinal tract colonization with antimicrobial-resistant enteric bacteria, but they cannot be rapidly collected. Perianal swab specimens can be collected more quickly and efficiently, but data evaluating their suitability as a specimen type for this purpose are sparse. We performed selective culture for extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) and fluoroquinolone- resistant Enterobacterales (FQRE)…

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The Hidden Crisis in the Times of COVID-19: Critical Shortages of Medical Laboratory Professionals in Clinical Microbiology

August 2, 2022

ABSTRACT The COVID pandemic has put a spotlight on laboratory medicine,showcasing how vital diagnostic testing is for society and the health care system.It has also brought to light and accelerated the critical shortage of trainedand experienced laboratory personnel that has been felt for decades. The needfor laboratory professionals is expected to grow by 11% between…

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Total Laboratory Automation for Rapid Detection and Identification of Microorganisms and Their Antimicrobial Resistance Profiles

August 2, 2022

At a time when diagnostic bacteriological testing procedures have become more complexand their associated costs are steadily increasing, the expected benefits of Totallaboratory automation (TLA) cannot just be a simple transposition of the traditionalmanual procedures used to process clinical specimens. In contrast, automation shoulddrive a fundamental change in the laboratory workflow and prompt users to…

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Validation of the Colibrí Instrument for Automated Preparation of MALDI-TOF MS Targets for Yeast Identification

August 2, 2022

ABSTRACT Recently, Copan (Italy) introduced the Colibrí instrument for automated colonypicking and preparation of matrix-assisted laser desorption ionization–time of flight (MALDI- TOF)target plates. Our study aimed to validate this system for yeasts as such testing has not beenperformed yet and is a missing link needed to implement the system for routine use. Fifty-fiveCandida strains were…

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Assessment of the Frequency of Coughing and Sneezing Triggered by Nasopharyngeal Swabbing in the Pandemic Setting

July 6, 2022

A variety of medical procedures are classified as aerosol generating. However there is no consensus on whether some procedures such as nasopharyngeal swabbing can generate aerosols. During specimen collection, the contact of the nasopharyngeal swab with the respiratory mucosa often triggers defense reflexes such as sneezing and coughing, which generate airborne particles. The accumulation and…

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Evaluation of the Colibrí from Copan for automated MALDI-TOF spotting

June 23, 2022
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[Poster] Evaluation Of Automated MALDI –TOF Target Plate Preparation

June 23, 2022
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[Poster] Automated colony picking and McFarland preparation using the Copan Colibri instrument is equivalent to manual McFarland preparations for antimicrobial susceptibility testing using the Vitek 2 system

June 23, 2022
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Evaluation of Commercially Available Viral Transport Medium (VTM) for SARS-CoV-2 Inactivation and Use in Point-of-Care (POC) Testing

November 11, 2021

Abstract: Critical to facilitating SARS-CoV-2 point-of-care (POC) testing is assurance that viruses present in specimens are inactivated onsite prior to processing. Here, we conducted experiments to determine the virucidal activity of commercially available Viral Transport Mediums (VTMs) to inactivate SARS-CoV-2. Independent testing methods for viral inactivation testing were applied, including a previously described World Health…

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A review of nasopharyngeal swab and saliva tests for SARS‐CoV‐2 infection: Disease timelines, relative sensitivities, and test optimization

November 11, 2021

Abstract Testing is an essential part of containment of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic. This review summarizes studies for SARS‐CoV‐2 infection and testing. Nasopharyngeal samples are best at sensitivity detection, especially in early stages of disease and in asymptomatic individuals. Current swab processing involves a 100‐ to 1000‐fold dilution of the…

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Sample collection and transport strategies to enhance yield, accessibility, and biosafety of COVID-19 RT-PCR testing

November 11, 2021

Abstract Introduction. Non-invasive sample collection and viral sterilizing buffers have independently enabled workflows for more widespread COVID-19 testing by reverse-transcriptase polymerase chain reaction (RT-PCR). Gap statement. The combined use of sterilizing buffers across non-invasive sample types to optimize sensitive, accessible, and biosafe sampling methods has not been directly and systematically compared. Aim. We aimed to…

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Beyond COVID-19—will self-sampling and testing become the norm?

November 11, 2021

In the fight against COVID-19, the general population in many countries has not been empowered to pursue diagnostic testing, but rather has been a subject to often frustrating and inadequate testing capacity. Diagnostics have been a cornerstone of the COVID-19 response globally, because strategies to contain and respond to the pandemic rely primarily on case…

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Inactivation of SARS-CoV-2 virus in saliva using a guanidium based transport medium suitable for RT-PCR diagnostic assays

November 4, 2021

Abstract BackgroundUpper respiratory samples used to test for SARS-CoV-2 virus may be infectious and presenta hazard during transport and testing. A buffer with the ability to inactivate SARS-CoV-2 atthe time of sample collection could simplify and expand testing for COVID-19 to non-conventionalsettings. MethodsWe evaluated a guanidium thiocyanate-based buffer, eNAT™ (Copan) as a possible transportand inactivation…

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Rapid and accurate eXDR screening: use Xpert Carba-R with FecalSwab

November 4, 2021

ABSTRACT The FecalSwab® displays high performances for stool culture, but it was not assessed for carbapenemase-producing Enterobacterales (CPE) screening. We assess the performances of the Xpert Carba-R v2® with the FecalSwab®. Using a collection of 12 CPE strains, the limit of detection was assessed at 158 CFU/swab [interquartile range 93–589]. In 2019, 1540 swabs were…

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Relative sensitivity of anterior nares and nasopharyngeal swabs for initial detection of SARS-CoV-2 in ambulatory patients: Rapid review and meta-analysis

July 22, 2021

Abstract Nasopharyngeal (NP) swabs are considered the “gold standard” for diagnosing SARS-CoV-2 infections, but anterior nares or mid-turbinate swabs (nasal swabs) are often used. We performed a meta-analysis comparing the sensitivity of nasal and nasopharyngeal swabs against a composite reference standard for the initial diagnosis of SARS-CoV-2 infection inambulatory patients. The study is registered on…

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Some of the studies in this database are independent scientific studies performed by third parties, while some of the studies were partially or entirely funded by COPAN. In addition to peer reviewed research this library also contains posters, which were presented at various scientific meetings, and may not have been subject to peer review.

Some of the studies found here may contain information about off label product use. Studies, product claims and availability may vary from country to country, and they are subject to varying regulatory requirements. Always refer to product labeling, package inserts and safety data sheets for the appropriate use of the products.