study-con@2x

Scientific Study Library

Thank you for visiting COPAN's Scientific Studies Library, your online resource for proof sources related to COPAN products as well as many other aspects of sample collection and transport, automation, food and pharmaceutical testing, forensic and genetic collection and more!

Comparison of Results Obtained with the FilmArray GI Panel using rectal Swabs and Cary-Blair Stool from Patients with Gastroenteritis in the Pediatric Emergency Department

Automated Scoring of Chromogenic Media for the Detection of MRSA Using the WASPLab Image Analysis Software

Comparison of the Copan ESwab System with an Agar Swab Transport System for Maintenance of Fastidious Anaerobic Bacteria Viability

Automation in the Clinical Microbiology Laboratory

Latest Studies:

Is Nasopharyngeal Swab Comparable With Nasopharyngeal Aspirate to Detect SARS-CoV-2 in Children?

October 22, 2020

To the Editors: In December 2019 appeared in China a novel coronavirus, designated as SARS-CoV-2, responsible for a pandemic respiratory disease, known as coronavirus disease, with the Italian outbreak from February 2020. Children appear to have milder symptoms and less severe disease.1 The tests currently used for the direct identification of SARS-CoV-2include specimens taken from…

Read More

NASAL SWAB AS PREFERRED CLINICAL SPECIMEN FOR COVID-19 TESTING IN CHILDREN

October 22, 2020

Abstract: The first pediatric study demonstrating significantly higherpositivity rate of nasal (mid-turbinate) swab testing over oropharyngealswab testing in detecting SARS-CoV-2 (Fisher exact test 0.046, Cohen K0.43, confidence interval 95%, 0.014–0.855). Benefits might include lowercollection-related hazard for healthcare workers. We recommend it as preferred choice for swab-based SARS-CoV-2 testing in children.

Read More

Evaluation of Saline, Phosphate-Buffered Saline, and Minimum Essential Medium as Potential Alternatives to Viral Transport Media for SARS-CoV-2 Testing

October 22, 2020

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has caused a global pandemic since being discovered in late 2019. In response, clinical microbiology and public health laboratories have worked to develop, validate, and implement molecular assays to detect SARS-CoV-2 from respiratory samples. The preferred and most commonly collected…

Read More

A Laboratory Risk Assessment During the Coronavirus (COVID-19) Pandemic

October 22, 2020

The novel coronavirus known as SARS CoV-2, the cause of COVID-19 has changed our lives. Social distancing and working from home have been recommended to flatten the epidemiologic curve for infections. With limited healthcare capacity, a pandemic like COVID-19 can overwhelm a medical system. Worldwide, governments are taking actions to minimize the impact on healthcare…

Read More

Performing the nasopharyngeal and oropharyngeal swab for. 2019-novel coronavirus (SARS-CoV-2) safely: How to dress, undress, and technical notes

October 22, 2020

Abstract Background: To show how to safely perform nasopharyngeal and/or oropharyngeal swabs for 2019-novel coronavirus. Methods: The video describes in detail the dressing and undressing procedures of health personnel, with the appropriate personal protective equipment. Technical notes for the execution of the nasopharyngeal and oropharyngeal swab are also provided to avoid sampling errors. Results: The…

Read More

Suboptimal Biological Sampling as a Probable Cause of False-Negative COVID-19 Diagnostic Test Results

October 22, 2020

False-negative severe acute respiratory syndrome coronavirus 2 test results can negatively impact the clinical and public health response to coronavirus disease 2019 (COVID-19). We used droplet digital polymerase chain reaction (ddPCR) to demonstrate that human DNA levels, a stable molecular marker of sampling quality, were significantly lower in samples from 40 confirmed or suspected COVID-19…

Read More

Swabs Collected by Patients or Health Care Workers for SARS-CoV-2 Testing

October 22, 2020

To the Editor: The early medical response to the Covid-19 pandemic in the United States was limited in part by the availability of testing. Health care workers collected a swab sample from the patients’ oropharynx or nasopharynx according to testing guidelines for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. This procedure potentially increased…

Read More

Clinical characteristics and risk factors for Clinical characteristics and risk factors for coronavirus disease 2019 (COVID-19) among patients under investigation in Thailand

October 22, 2020

Abstract To manage coronavirus disease 2019 (COVID-19), a national health authority has implemented a case definition of patients under investigation (PUIs) to guide clinicians’ diagnoses. We aimed to determine characteristics among all PUIs and those with and without COVID-19. We retrospectively reviewed clinical characteristics and risk factors for laboratory confirmed COVID-19 cases among PUIs at…

Read More

Isolation and characterization of severe acute respiratory syndrome coronavirus 2 in Turkey

October 22, 2020

Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and associated with severe respiratory illness emerged in Wuhan, China, in late 2019. The virus has been able to spread promptly across all continents in the world. The current pandemic has posed a great threat to public health concern and safety.…

Read More

Comparison of Abbott ID Now, DiaSorin Simplexa, and CDC FDA Emergency Use Authorization Methods for the Detection of SARS-CoV-2 from Nasopharyngeal and Nasal Swabs from Individuals Diagnosed with COVID-19

October 22, 2020

Dozens of in vitro diagnostics (IVDs) have received emergency use authorization (EUA) from the U.S. Food and Drug Administration (FDA) for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but how well these assays perform using clinical specimens has hardly been studied. This study compared the positive percent agreement (PPA) of ID Now…

Read More

Comparison of Two Commercial Molecular Tests and a Laboratory-Developed Modification of the CDC 2019-nCoV Reverse Transcriptase PCR Assay for the Detection of SARSCoV-2

October 22, 2020

ABSTRACT We compared the ability of 2 commercial molecular amplification assays (RealTime SARS-CoV-2 on the m2000 [abbreviated ACOV; Abbott] and ID Now COVID-19 [abbreviated IDNOW; Abbott]) and a laboratory-developed test (modified CDC 2019-nCoV reverse transcriptase PCR [RT-PCR] assay with RNA extraction by eMag [bioMérieux] and amplification on QuantStudio 6 or ABI 7500 real-time PCR system…

Read More

Open Development and Clinical Validation of Multiple 3DPrinted Nasopharyngeal Collection Swabs: Rapid Resolution of a Critical COVID-19 Testing Bottleneck

October 22, 2020

ABSTRACT The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a severe international shortage of the nasopharyngeal swabs that are required for collection of optimal specimens, creating a critical bottleneck blocking clinical laboratories’ ability to perform high-sensitivity virological testing for SARS-CoV-2. To address this crisis, we designed and executed an innovative,…

Read More

Performance of Abbott ID Now COVID-19 Rapid Nucleic Acid Amplification Test Using Nasopharyngeal Swabs Transported in Viral Transport Media and Dry Nasal Swabs in a New York City Academic Institution

October 22, 2020

ABSTRACT The recent emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has posed formidable challenges for clinical laboratories seeking reliable laboratory diagnostic confirmation. The swift advance of the crisis in the United States has led to Emergency Use Authorization (EUA) facilitating the availability of molecular diagnostic assays without the more rigorous examination…

Read More

Nasal Swab Sampling for SARS-CoV-2: a Convenient Alternative in Times of Nasopharyngeal Swab Shortage

October 22, 2020

Nasopharyngeal swab is the reference sampling method to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as recommended by the World Health Organization (WHO) (1). However, nasal specimens may have a slightly lower sensitivity than nasopharyngeal specimens (2, 3). We herein validated an alternative procedure to collect nasal secretions with a swab routinely used in…

Read More

Comparison of Copan ESwab and FLOQSwab for COVID-19 Diagnosis: Working around a Supply Shortage

October 22, 2020

On 16 March 2020, the WHO Director-General stated, “You cannot fight a fire blindfolded. And we cannot stop this [COVID-19] pandemic if we don’t know who is infected. We have a simple message for all countries: test, test, test. Test every suspected case” (https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19—16-march-2020). This strategy hinges on the availability of appropriate, validated collection and…

Read More

Some of the studies in this database are independent scientific studies performed by third parties, while some of the studies were partially or entirely funded by COPAN. In addition to peer reviewed research this library also contains posters, which were presented at various scientific meetings, and may not have been subject to peer review.

Some of the studies found here may contain information about off label product use. Studies, product claims and availability may vary from country to country, and they are subject to varying regulatory requirements. Always refer to product labeling, package inserts and safety data sheets for the appropriate use of the products.